INOs-IN-6
INOs-IN-6 is an anti-inflammatory agent. iNOs-IN-6 inhibits NF-κB, iNOS, and MAPK expression (IC50: 0.2-0.62 μM) . iNOs-IN-6 reduces IL-6, TNF-α, and IL-1β pro-inflammatory mediators levels (IC50: 0.4-0.69 μM) [1].
Product Specifications
UNSPSC
12352005
Target
Interleukin Related; NF-κB; NO Synthase; p38 MAPK
Related Pathways
Immunology/Inflammation; MAPK/ERK Pathway; NF-κB
Field of Research
Inflammation/Immunology
Smiles
ClC1=CC=C(NC(C2=C(C)NC(NC2C3=CC4=C(C=CC=C4)S3)=O)=O)C=C1
Molecular Formula
C20H16ClN3O2S
Molecular Weight
397.88
References & Citations
[1]Ahmed R. Ali, et al. Design, synthesis, and biological evaluation of new tetrahydropyrimidine derivatives as multitarget anti-inflammatory agents. European Journal of Medicinal Chemistry Reports. Volume 13, April 2025, 100259
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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