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E3 ligase Ligand 59

E3 ligase Ligand 59 (Compound 20e) is the E3 ubiquitin ligase ligand of FDU73 (HY-173125) . E3 ligase Ligand 59 can be used to synthesize PROTACs[1].

Product Specifications

CAS Number

[2913165-27-0]

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C1CCC(C2=CN=C(N3CCC(CC=O)CC3)C=C2)C(N1)=O

Molecular Formula

C17H21N3O3

Molecular Weight

315.37

References & Citations

[1]Lin Y, et al. Design, synthesis, and biological evaluation of novel BTK-targeting proteolysis targeting chimeras (PROTACs) with enhanced pharmacokinetic properties. Eur J Med Chem. 2025 May 5;289:117420.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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