AR ligand-39

AR ligand-39, an androgen receptor (AR) ligand, is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC) . AR ligand-39 can be used for synthesis PROTAC AR Degrader-10 (HY-173372) [1].

Product Specifications

CAS Number

[2156591-18-1]

UNSPSC

12352005

Target

Androgen Receptor; Ligands for Target Protein for PROTAC

Related Pathways

PROTAC; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

ClC1=C(C#N)C=CC(O[C@H]2C(C)(C)[C@H](NC(C3=CC=C(N4CCNCC4)N=C3)=O)C2(C)C)=C1

Molecular Formula

C25H30ClN5O2

Molecular Weight

467.99

References & Citations

[1]Zhang L, et al. Predicting PROTAC-targeted Degradation and Designing Androgen Receptor Degraders with AiPROTAC[J]. bioRxiv, 2025: 2025.02. 26.640266.