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Anticancer agent 270

Anticancer agent 270 (Compound 8e) is an inhibitor that acts on tubulin. Its IC50 value against MCF-7 breast cancer cells is 1.02 μM. Through a dual mechanism of action, namely inducing Apoptosis and destabilizing microtubules, it exerts significant anti-proliferative activity against breast cancer cells. Anticancer agent 270 can be applied to research in the field of cancer[1].

Product Specifications

UNSPSC

12352005

Target

Microtubule/Tubulin

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Field of Research

Cancer

Smiles

CC1=CC=C2C(C(C(C3=NN=C(SCC(C4=CC(OC)=C(OC)C(OC)=C4)=O)N3)=CO2)=O)=C1

Molecular Formula

C23H21N3O6S

Molecular Weight

467.49

References & Citations

[1]Saadh M J, et al. Design and synthesis of chromene-triazole hybrids via recyclable magnetic nanocatalyst: Potent dual-acting anticancer agents targeting apoptotic and microtubule dynamics[J]. Journal of Molecular Structure, 2025, 1338: 142093.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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