E3 Ligase Ligand-linker Conjugate 174
E3 Ligase Ligand-linker Conjugate 174 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 174 can be used to synthesize TYD-68 (HY-173357) [1].
Product Specifications
CAS Number
[2703765-01-7]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
NC1CCC(CC1)NC2=CC3=C(C=C2)C(N(C3=O)C4C(NC(CC4)=O)=O)=O
Molecular Formula
C19H22N4O4
Molecular Weight
370.40
References & Citations
[1]Xiong S, et al. Discovery of a Highly Potent and Selective Tyrosine Kinase 2 (TYK2) Degrader with In Vivo Therapeutic Efficacy in a Murine Psoriasis Model. J Med Chem. 2025 Apr 10;68 (7) :7560-7578.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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