RCB18350

RCB18350 is an antituberculosis agent that belongs to the class of isoxazole derivatives. RCB18350 has bacteriostatic activity and inhibits the growth of Mycobacterium tuberculosis with an MIC of 1.25 μg/mL. RCB18350 is effective against multidrug-resistant Mycobacterium tuberculosis (MDR-TB) clinical isolates, slow-growing mycobacteria such as Mycobacterium bovis BCG and Mycobacterium avium[1].

Product Specifications

CAS Number

[3052630-27-7]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

CCOC(C1=NOC(CCCSC2=CC=C(C3=NOC(C(F)(F)F)=N3)C=C2C)=C1)=O

Molecular Formula

C19H18F3N3O4S

Molecular Weight

441.42

References & Citations

[1]Recchia D, et al. Mycobacterium tuberculosis Sulfate Ester Dioxygenase Rv3406 Is Able to Inactivate the RCB18350 Compound. ACS Infect Dis. 2025 Apr 11;11 (4) :986-997.