BRCA2-RAD51-IN-2

BRCA2-RAD51-IN-2 (compound S-35d) is a BRCA2-RAD51 inhibitor and inhibits homologous recombination repair in combination with 10 µM olaparib (HY-10162) [1].

Product Specifications

UNSPSC

12352005

Target

RAD51

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C(CC)N(N=C(C1=C(C2=CC=CC=C2)C(C=C(Cl)C=C3)=C3NC1=O)C4)[C@@H]4C5=CC=C(OC)C=C5

Molecular Formula

C28H24ClN3O3

Molecular Weight

485.96

References & Citations

[1]Mirco Masi, et al. Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity. Cell Death Discov. 2025 Mar 16;11 (1) :106.