MAO-B-IN-42
MAO-B-IN-42 (Compound 4f) is a selective and reversible inhibitor of monoamine oxidase-B (MAO-B) with an IC50 value of 0.184 μM. MAO-B-IN-42 helps maintain the levels of neurotransmitters by blocking the oxidative deamination of monoamines catalyzed by MAO-B. MAO-B-IN-42 is promising for research of Parkinson's disease[1].
Product Specifications
CAS Number
[2568016-10-2]
UNSPSC
12352005
Target
Monoamine Oxidase
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
OC1=CC=C(C2=CC=C3N=C(C4=CC=CC(F)=C4)OC3=C2)C=C1
Molecular Formula
C19H12FNO2
Molecular Weight
305.30
References & Citations
[1]Lee H, et al. 2, 6‐Diarylbenzo [d] oxazoles as MAO‐B inhibitors for the treatment of Parkinson's disease[J]. Bulletin of the Korean Chemical Society.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-B
Curated Selection
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