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BRD4 degrader-6

BRD4 degrader-6 is a dimeric BDR4 PROTAC degrader (DC50: [1].

Product Specifications

CAS Number

[3055207-38-7]

UNSPSC

12352005

Target

Epigenetic Reader Domain; PROTACs

Related Pathways

Epigenetics; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

ClC1=CC=C(C=C1)C2=N[C@H](C3=NN=C(N3C4=C2C(C)=C(S4)C)C)CC(NCC[C@@]56[C@@H]7C[C@H](C[C@@H]5OB(O6)C8=C(C=CC=C8)CCC(N[C@H](C(N9C[C@@H](C[C@H]9C(NCC%10=CC=C(C=C%10)C%11=C(N=CS%11)C)=O)O)=O)C(C)(C)C)=O)C7(C)C)=O

Molecular Formula

C61H71BClN9O7S2

Molecular Weight

1152.67

References & Citations

[1]Harry Finch, et al. Dimer compounds. England. WO2024175905 2024-08-29

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

BRD4

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