FAP-IN-5

FAP-IN-5 (Compound 4a) is an FAP inhibitor with an IC50 of 1.7 nM. FAP-IN-5 can be used in the research of tumor positron emission tomography (PET) imaging[1].

Product Specifications

UNSPSC

12352005

Target

FAP

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Smiles

FCCN1N=NC(CN2CCN(CCCN(C)C3=CC=C(N=CC=C4C(NCC(C5CC(F)(F)C[C@H]5C#N)=O)=O)C4=C3)CC2)=C1

Molecular Formula

C31H38F3N9O2

Molecular Weight

625.69

References & Citations

[1]Köchel R, et al. Synthesis of piperazine-based fluorinated fibroblast activation protein inhibitors for the development of a novel 18F-labeled PET imaging probe. Eur J Med Chem. 2025 Jun 5;290:117513.