FAP-IN-5
FAP-IN-5 (Compound 4a) is an FAP inhibitor with an IC50 of 1.7 nM. FAP-IN-5 can be used in the research of tumor positron emission tomography (PET) imaging[1].
Product Specifications
UNSPSC
12352005
Target
FAP
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
FCCN1N=NC(CN2CCN(CCCN(C)C3=CC=C(N=CC=C4C(NCC(C5CC(F)(F)C[C@H]5C#N)=O)=O)C4=C3)CC2)=C1
Molecular Formula
C31H38F3N9O2
Molecular Weight
625.69
References & Citations
[1]Köchel R, et al. Synthesis of piperazine-based fluorinated fibroblast activation protein inhibitors for the development of a novel 18F-labeled PET imaging probe. Eur J Med Chem. 2025 Jun 5;290:117513.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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