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Ferroptosis-IN-19

Ferroptosis-IN-19 (compound C18) is a strong cellular ferroptosis inhibitor with an IC50 value of 0.097 μM. Ferroptosis-IN-19 shows high metabolic stability and favorable BBB permeability prediction. Ferroptosis-IN-19 has in vivo neuroprotection against ischemic brain injury in mice[1].

Product Specifications

CAS Number

3025114-13-7

UNSPSC

12352005

Target

Ferroptosis

Related Pathways

Apoptosis

Applications

Neuroscience-Neurodegeneration

Field of Research

Cardiovascular Disease

Purity

98.92

Smiles

ClC1=C(OC)C=CC(NC2=C(C3CCCCC3)N=C4N2C=CC=C4)=C1

Molecular Formula

C20H22ClN3O

Molecular Weight

355.86

References & Citations

[1]Jilei Wang, et al. Identification of imidazo[1,2-a]pyridine-3-amine as a novel drug-like scaffold for efficious ferroptosis inhibition in vivo. Eur J Med Chem. 2025 Jun 5:290:117516.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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