Mpro/PLPro-IN-2
Mpro/PLPro-IN-2 (Compound 22l) is a non-covalent competitive dual inhibitor of the papain-like protease and main protease of SARS-CoV-2, with a Ki of 0.2 μM for the papain-like protease and a Ki of 1.1 μM for the main protease[1]. Mpro/PLPro-IN-2 can be used in the research field of anti-SARS-CoV-2[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV; Virus Protease
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(NNC1=NC(C)=C(C(OCC)=O)S1)/C=C/C2=CC=CC=C2
Molecular Formula
C16H17N3O3S
Molecular Weight
331.39
References & Citations
[1]Alli VJ, et al. Development of acylhydrazone linked thiazoles as non-covalent dual inhibitors of SARS-CoV-2 proteases. Eur J Med Chem. 2025 Jun 5;290:117509.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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