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Aβ aggregation-IN-2

Aβ aggregation-IN-2 (Compound 8i) is an inhibitor of amyloid-β protein (Aβ42) aggregation, showing approximately 91% inhibition of Aβ42 aggregation at 25 μM. It also exhibits Aβ42 disaggregation effects and antioxidant activity. Aβ aggregation-IN-2 can be used for research in the field of Alzheimer's disease[1].

Product Specifications

UNSPSC

12352005

Target

Amyloid-β

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

OC1=CC=C(CN2C3=C(C=CC=C3)[Se]C4=CC=CC=C24)C=C1

Molecular Formula

C19H15NOSe

Molecular Weight

352.29

References & Citations

[1]Hefny AA, et al. Novel Phenoselenazines as Amyloid-β Aggregation Inhibitors. ACS Med Chem Lett. 2025 Mar 17;16 (4) :567-574.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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