Aβ aggregation-IN-2
Aβ aggregation-IN-2 (Compound 8i) is an inhibitor of amyloid-β protein (Aβ42) aggregation, showing approximately 91% inhibition of Aβ42 aggregation at 25 μM. It also exhibits Aβ42 disaggregation effects and antioxidant activity. Aβ aggregation-IN-2 can be used for research in the field of Alzheimer's disease[1].
Product Specifications
UNSPSC
12352005
Target
Amyloid-β
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
OC1=CC=C(CN2C3=C(C=CC=C3)[Se]C4=CC=CC=C24)C=C1
Molecular Formula
C19H15NOSe
Molecular Weight
352.29
References & Citations
[1]Hefny AA, et al. Novel Phenoselenazines as Amyloid-β Aggregation Inhibitors. ACS Med Chem Lett. 2025 Mar 17;16 (4) :567-574.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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