CYP19A1-IN-1
CYP19A1-IN-1 (Compound 9) is a CYP19A1 inhibitor with an IC50 of 271 nM. CYP19A1-IN-1 inhibits the activity of converting androgens to estrogens by binding to CYP19A1. CYP19A1-IN-1 can be used in the research of sex hormone-related diseases such as estrogen-dependent breast cancer[1].
Product Specifications
CAS Number
[889959-22-2]
UNSPSC
12352005
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Endocrinology
Smiles
CC(C1=CC=C(C=C1)N2C=CN=C2)NC(C3=CC4=CC(Cl)=CC=C4OC3=O)=O
Molecular Formula
C21H16ClN3O3
Molecular Weight
393.82
References & Citations
[1]Liu S, et al. Integrated Virtual Screening Approach Identifies New CYP19A1 Inhibitors. J Chem Inf Model. 2025 Mar 19.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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