AIC263282
AIC263282 is a potent Hepatitis B Virus (HBV) capsid assembly modulator with an EC50 of 3.8 nM. AIC263282 shows an IC50 of 61 nM for hERG. AIC263282 exhibits activity against viral replication and hepatitis B surface antigen (HBsAG) on primary human hepatocytes[1].
Product Specifications
UNSPSC
12352005
Target
HBV; Potassium Channel
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel
Field of Research
Infection
Smiles
CCC1=C2C(NC(C(N3[C@H](C)CN(C(C(NC4(COC4)C)=O)=O)CC3)=O)=C2)=CC(F)=C1
Molecular Formula
C22H27FN4O4
Molecular Weight
430.47
References & Citations
[1]Bernhard Lesch, et al. Discovery of AIC263282, a Hepatitis B Virus Capsid Assembly Modulator Ready for Candidate Profiling. J Med Chem. 2025 Mar 27;68 (6) :6361-6371.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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