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FtsZ-IN-13

FtsZ-IN-13 (Compound C11) is an inhibitor of temperature-sensitive mutant Z (FtsZ), with IC50 values of 47.97, 34 μM against FtsZSa and FtsZPa, respectively. FtsZ-IN-13 has a notable antimicrobial activity against S. aureus (minimum inhibitory concentration value of 2 μg/mL), cystic fibrosis S. aureus clinical isolates, and methicillin-resistant S. aureus (MRSA) strains. FtsZ-IN-13 can be used for antimicrobial resistance study[1].

Product Specifications

CAS Number

[914357-88-3]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=S1(C2=CC=CC=C2C(SC3=NN=C(O3)CC4=CC=C(C=C4)OC)=C1)=O

Molecular Formula

C18H14N2O4S2

Molecular Weight

386.44

References & Citations

[1]Sciò P, et al. Identification of a New FtsZ Inhibitor by Virtual Screening, Mechanistic Insights, and Structure-Activity Relationship Analyses. ACS Infect Dis. 2025 Apr 11;11 (4) :998-1007.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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