FtsZ-IN-13
FtsZ-IN-13 (Compound C11) is an inhibitor of temperature-sensitive mutant Z (FtsZ), with IC50 values of 47.97, 34 μM against FtsZSa and FtsZPa, respectively. FtsZ-IN-13 has a notable antimicrobial activity against S. aureus (minimum inhibitory concentration value of 2 μg/mL), cystic fibrosis S. aureus clinical isolates, and methicillin-resistant S. aureus (MRSA) strains. FtsZ-IN-13 can be used for antimicrobial resistance study[1].
Product Specifications
CAS Number
[914357-88-3]
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=S1(C2=CC=CC=C2C(SC3=NN=C(O3)CC4=CC=C(C=C4)OC)=C1)=O
Molecular Formula
C18H14N2O4S2
Molecular Weight
386.44
References & Citations
[1]Sciò P, et al. Identification of a New FtsZ Inhibitor by Virtual Screening, Mechanistic Insights, and Structure-Activity Relationship Analyses. ACS Infect Dis. 2025 Apr 11;11 (4) :998-1007.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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