PARP7-IN-24
PARP7-IN-24 (compound 44) is a potent PARP7 inhibitor with an EC50 of 0.375 nM for pSTAT1 in NCI-H1373 cells. PARP7-IN-24 has the potential for cancer research[1].
Product Specifications
CAS Number
[3072866-54-4]
UNSPSC
12352005
Target
PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
O=C1NN=CC(O[C@@H](C)C[C@H](CN2C(C(C(F)=C(F)C(C3=NC=C(OC)C=N3)=C4)=C4C=C2)=O)F)=C1C(F)(F)F
Molecular Formula
C24H19F6N5O4
Molecular Weight
555.43
References & Citations
[1]Jonah J. CHANG, ET AL. Parp7 inhibitors. WO2025024663A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP7
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