PARP7-IN-23
PARP7-IN-23 (compound 56) is a potent PARP7 inhibitor with an EC50 of 0.915 nM for pSTAT1 in NCI-H1373 cells. PARP7-IN-23 has the potential for cancer research[1].
Product Specifications
CAS Number
[3071875-24-3]
UNSPSC
12352005
Target
PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1NN=CC(O[C@@H]2C[C@H](CN3C(C(C(F)=C(F)C(C4=NC=C(C(F)(F)C)C=N4)=C5)=C5C=C3)=O)CCC2)=C1C(F)(F)F
Molecular Formula
C27H22F7N5O3
Molecular Weight
597.48
References & Citations
[1]Jayaraman Chandrasekhar, et al. Parp7 inhibitors. US20250100998A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP7
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