E3 Ligase Ligand-linker Conjugate 173
E3 Ligase Ligand-linker Conjugate 173 is an E3 Ligase Ligand-Linker Conjugate. E3 Ligase Ligand-linker Conjugate 173 can be used to synthesize YN14-H (HY-173250) to induce apoptosis and inhibits migration, and exert antitumor activity in vivo[1].
Product Specifications
CAS Number
[2907682-88-4]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C([C@H]1N(C([C@@H](NC(C2(F)CC2)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3OCCCCl
Molecular Formula
C29H38ClFN4O5S
Molecular Weight
609.15
References & Citations
[1]Sun Sy, et al. Rational design of VHL-recruiting KRASG12C proteolysis-targeting chimeras based on molecular dynamics simulation. Available online 20 February 2025, 110992.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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