Val-Ala-PAB-SN38
Val-Ala-PAB-SN38 is a drug-linker conjugate for ADC, composed of ADC linker Val-Ala-PAB and SN38 (HY-13704), which is the active metabolite of the Topoisomerase I inhibitor Irinotecan (HY-16562).
Product Specifications
CAS Number
3025787-76-9
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1N2C(C(C(C2)=C(C3=C4)CC)=NC3=CC=C4O)=CC5=C1COC([C@@]5(CC)OC(OCC6=CC=C(C=C6)NC([C@H](C)NC([C@@H](N)C(C)C)=O)=O)=O)=O
Molecular Formula
C38H41N5O9
Molecular Weight
711.76
References & Citations
[1]Paul Joseph Mark JACKSON, et al. Antibody-drug conjugates. WO2024013724A1. 2023-07-15
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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