Pseudorabies virus-IN-1
Pseudorabies virus-IN-1 is a potent pseudorabies virus (PRV) inhibitor (EC50: 0.29 nM) . Pseudorabies virus-IN-1 inhibits PRV replication by targeting PRV deoxyribonucleic acid polymerase (DNA pol) . Pseudorabies virus-IN-1 can effectively inhibit PRV replication at low concentrations (MIC80: 1.6-8 nM) . Pseudorabies virus-IN-1 can be used to study PRV infection[1].
Product Specifications
UNSPSC
12352005
Target
DNA/RNA Synthesis; HSV
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
O=C1C(C(NCC2=CC(Cl)=CC=C2F)=O)=CN(C3=CC=CC=C3)C4=C1C=C(F)C(N5CCNCC5)=C4
Molecular Formula
C27H23ClF2N4O2
Molecular Weight
508.95
References & Citations
[1]Wei L, et al. Rapid discovery of pseudorabies virus inhibitors repurposed from the antimicrobial agent ciprofloxacin. Eur J Med Chem. 2025 May 5;289:117490.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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