Pseudorabies virus-IN-1

Pseudorabies virus-IN-1 is a potent pseudorabies virus (PRV) inhibitor (EC50: 0.29 nM) . Pseudorabies virus-IN-1 inhibits PRV replication by targeting PRV deoxyribonucleic acid polymerase (DNA pol) . Pseudorabies virus-IN-1 can effectively inhibit PRV replication at low concentrations (MIC80: 1.6-8 nM) . Pseudorabies virus-IN-1 can be used to study PRV infection[1].

Product Specifications

UNSPSC

12352005

Target

DNA/RNA Synthesis; HSV

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Field of Research

Infection

Smiles

O=C1C(C(NCC2=CC(Cl)=CC=C2F)=O)=CN(C3=CC=CC=C3)C4=C1C=C(F)C(N5CCNCC5)=C4

Molecular Formula

C27H23ClF2N4O2

Molecular Weight

508.95

References & Citations

[1]Wei L, et al. Rapid discovery of pseudorabies virus inhibitors repurposed from the antimicrobial agent ciprofloxacin. Eur J Med Chem. 2025 May 5;289:117490.