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Antileishmanial agent-33

Antileishmanial agent-33 (4e), a hybrid compound of grandisin and machilin G, shows moderate activity on promastigotes (IC50 of 38.1 μM) . Antileishmanial agent-33 (4e) shows potential as an antileishmanial agent for the research of cutaneous leishmaniasis (CL) [1].

Product Specifications

UNSPSC

12352005

Target

Parasite

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Smiles

COC1=C(OC)C(OC)=C(Cl)C(C2=NOC(C3=CC=C(OCO4)C4=C3)=C2)=C1

Molecular Formula

C19H16ClNO6

Molecular Weight

389.79

References & Citations

[1]Amarith R das Neves, et al. Exploring chloro-isoxazole compounds inspired on tetrahydrofuran neolignans as promising antileishmanial agents. Eur J Med Chem. 2025 Jun 5:290:117478.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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