TNF-α-IN-22
TNF-α-IN-22 (Compound 30) is a TNFα inhibitor. It can induce Apoptosis by inhibiting the downregulation of IkBα induced by TNFα and blocking the cell cycle. TNF-α-IN-22 can be used in the research of triple-negative breast cancer[1].
Product Specifications
CAS Number
2251689-60-6
UNSPSC
12352005
Target
Apoptosis; TNF Receptor
Related Pathways
Apoptosis
Field of Research
Cancer
Smiles
COC1=CC2=CC=CC=C2C(/C=C/[N+]([O-])=O)=C1
Molecular Formula
C13H11NO3
Molecular Weight
229.23
References & Citations
[1]Qu X, et al. Aromatic nitroolefin with inhibition efficacy in triple-negative breast cancer cells by dual targeting RXRα and tubulins. Eur J Med Chem. 2025 May 5;289:117486.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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