TNF-α-IN-22

TNF-α-IN-22 (Compound 30) is a TNFα inhibitor. It can induce Apoptosis by inhibiting the downregulation of IkBα induced by TNFα and blocking the cell cycle. TNF-α-IN-22 can be used in the research of triple-negative breast cancer[1].

Product Specifications

CAS Number

[2251689-60-6]

UNSPSC

12352005

Target

Apoptosis; TNF Receptor

Related Pathways

Apoptosis

Field of Research

Cancer

Smiles

COC1=CC2=CC=CC=C2C(/C=C/[N+]([O-])=O)=C1

Molecular Formula

C13H11NO3

Molecular Weight

229.23

References & Citations

[1]Qu X, et al. Aromatic nitroolefin with inhibition efficacy in triple-negative breast cancer cells by dual targeting RXRα and tubulins. Eur J Med Chem. 2025 May 5;289:117486.