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CDK2-IN-43

CDK2-IN-43 (Compound 3a) is a CDK2-cyclin E2 inhibitor with an IC50 value of 6.0 nM. CDK2-IN-43 can be used in the research of the anti-cancer field[1].

Product Specifications

UNSPSC

12352005

Target

CDK

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

CC1=CC(C)=C(CNC2=C3C(N(C)C=N3)=NC(N[C@@H](CO)C(C)C)=N2)C=N1

Molecular Formula

C19H27N7O

Molecular Weight

369.46

References & Citations

[1]Zhang Y, et al. Development of 9H-purine scaffold as novel CDK2 inhibitors: Design, synthesis, and biological evaluation. Bioorg Med Chem Lett. 2025 Mar 7;122:130166.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK2

Frequently Asked Questions

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