CDK2-IN-43
CDK2-IN-43 (Compound 3a) is a CDK2-cyclin E2 inhibitor with an IC50 value of 6.0 nM. CDK2-IN-43 can be used in the research of the anti-cancer field[1].
Product Specifications
UNSPSC
12352005
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
CC1=CC(C)=C(CNC2=C3C(N(C)C=N3)=NC(N[C@@H](CO)C(C)C)=N2)C=N1
Molecular Formula
C19H27N7O
Molecular Weight
369.46
References & Citations
[1]Zhang Y, et al. Development of 9H-purine scaffold as novel CDK2 inhibitors: Design, synthesis, and biological evaluation. Bioorg Med Chem Lett. 2025 Mar 7;122:130166.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2
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