PRRSV-IN-1

PRRSV-IN-1 (Compound 4s) is a nsp4 protease inhibitor targeting PRRSV, exhibiting an EC50 of 0.45 μM against PRRSV. It binds to the nsp4 protease with a Kd value of 29.24 pM and inhibits nsp4 protease activity with an IC50 of 80.36 pM. PRRSV-IN-1 can be used for research in the field of antiviral infections[1].

Product Specifications

CAS Number

[801220-43-9]

UNSPSC

12352005

Target

Virus Protease

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

O=C1C(O)=C(OC2=CC(Br)=CC=C21)C3=CC=C(C=C3)N(CC)CC

Molecular Formula

C19H18BrNO3

Molecular Weight

388.26

References & Citations

[1]Wang ZZ, et al. Discovery of Flavonol derivatives as porcine reproductive and respiratory syndrome virus inhibitors. Bioorg Med Chem Lett. 2025 Jun 1;121:130162.