PRRSV-IN-1
PRRSV-IN-1 (Compound 4s) is a nsp4 protease inhibitor targeting PRRSV, exhibiting an EC50 of 0.45 μM against PRRSV. It binds to the nsp4 protease with a Kd value of 29.24 pM and inhibits nsp4 protease activity with an IC50 of 80.36 pM. PRRSV-IN-1 can be used for research in the field of antiviral infections[1].
Product Specifications
CAS Number
[801220-43-9]
UNSPSC
12352005
Target
Virus Protease
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C1C(O)=C(OC2=CC(Br)=CC=C21)C3=CC=C(C=C3)N(CC)CC
Molecular Formula
C19H18BrNO3
Molecular Weight
388.26
References & Citations
[1]Wang ZZ, et al. Discovery of Flavonol derivatives as porcine reproductive and respiratory syndrome virus inhibitors. Bioorg Med Chem Lett. 2025 Jun 1;121:130162.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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