Carbonic anhydrase inhibitor 29

Carbonic anhydrase inhibitor 29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX (CA IX) and XII (CA XII), with inhibition constants (Ki) of 26.6 nM for CA IX and 10.9 nM for CA XII. Carbonic anhydrase inhibitor 29 can be used in anticancer research[1].

Product Specifications

UNSPSC

12352005

Target

Carbonic Anhydrase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

ClC1=CC=C(C(CN(C2=CC=C(S(=O)(N)=O)C=C2)CC3=CC=CC=C3)=O)C=C1

Molecular Formula

C21H19ClN2O3S

Molecular Weight

414.91

References & Citations

[1]Elsayad KA, et al. Development of novel amino-benzenesulfonamide derivatives and their analogues as carbonic anhydrase inhibitors: Design, synthesis, anticancer activity assessment, and pharmacokinetic studies using UPLC-MS/MS. Bioorg Chem. 2025 Mar 5;159:108335.