Anticonvulsant agent 10
Anticonvulsant agent 10 (Compound 6d) is an inhibitor targeting the Keap1-Nrf2 interaction, with a potent ED50 of 0.04 mmol/kg. By inhibiting Keap1-Nrf2 binding and activating the Nrf2/ARE pathway, Anticonvulsant agent 10 exerts anticonvulsant and neuroprotective effects, making it suitable for research in antiepileptic and neuroprotective studies[1].
Product Specifications
UNSPSC
12352005
Target
Keap1-Nrf2
Related Pathways
NF-κB
Field of Research
Neurological Disease
Smiles
O=C(NC1=CC=NC=C1)C2(CCCCC2)NC3=CC=C(C=C3)OC
Molecular Formula
C19H23N3O2
Molecular Weight
325.40
References & Citations
[1]Abd-Allah WH, et al. Design and synthesis of novel cyclohexanecarboxamides with anticonvulsant effect by activating Nrf2-ARE pathway. Bioorg Chem. 2025 Mar 10;159:108357.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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