(E) -2,6-Di-tert-butyl-4- (4- (diethylamino) styryl) pyrylium (trifluoromethanesulfonate)
Selected Variant
HY-173163
Size: 1 Each
(E) -2,6-Di-tert-butyl-4- (4- (diethylamino) styryl) pyrylium (trifluoromethanesulfonate) (Compound 4a) is a Gram-negative outer membrane permeabilizer with synergistic antibacterial activity through the blockage on LptA/LptC interaction via targeting Met47 in LptA. (E) -2,6-Di-tert-butyl-4- (4- (diethylamino) styryl) pyrylium (trifluoromethanesulfonate) potentiates pol B against both wild-typed and MDR A. baumannii and E. coli strains. (E) -2,6-Di-tert-butyl-4- (4- (diethylamino) styryl) pyrylium (trifluoromethanesulfonate) can be used as antibiotic adjuvants against MDR Gram-negative bacteria[1].
Product Specifications
CAS Number
2811663-45-1
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=S(C(F)(F)F)([O-])=O.CCN(CC)C(C=C1)=CC=C1/C=C/C2=CC(C(C)(C)C)=[O+]C(C(C)(C)C)=C2
Molecular Formula
C26H36F3NO4S
Molecular Weight
515.63
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
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