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AChE/BChE-IN-26

AChE/BChE-IN-26 (Compound 20aa) is a cholinesterase inhibitor with IC50 values of 0.75 μM and 4.11 μM against eeAChE and eqBChE, respectively. AChE/BChE-IN-26 has antioxidant activity and can be used in the research of diseases such as Alzheimer's disease[1].

Product Specifications

UNSPSC

12352005

Target

Cholinesterase (ChE)

Related Pathways

Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

O=C(NCC1=CC(C(NCC2=CC=C(C(F)(F)F)C=C2)=O)=CC=C1)CSC3=NN4C(S3)=NC(C5=CC=C(C(F)(F)F)C=C5)=C4

Molecular Formula

C29H21F6N5O2S2

Molecular Weight

649.63

References & Citations

[1]Du W R, et al. Design, synthesis, biological evaluation, and in silico studies of imidazo [2, 1-b][1, 3, 4] thiadiazole derivatives as cholinesterase inhibitors. Medicinal Chemistry Research, 2025: 1-19.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE; BChE

Frequently Asked Questions

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