AChE/BChE-IN-26
AChE/BChE-IN-26 (Compound 20aa) is a cholinesterase inhibitor with IC50 values of 0.75 μM and 4.11 μM against eeAChE and eqBChE, respectively. AChE/BChE-IN-26 has antioxidant activity and can be used in the research of diseases such as Alzheimer's disease[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C(NCC1=CC(C(NCC2=CC=C(C(F)(F)F)C=C2)=O)=CC=C1)CSC3=NN4C(S3)=NC(C5=CC=C(C(F)(F)F)C=C5)=C4
Molecular Formula
C29H21F6N5O2S2
Molecular Weight
649.63
References & Citations
[1]Du W R, et al. Design, synthesis, biological evaluation, and in silico studies of imidazo [2, 1-b][1, 3, 4] thiadiazole derivatives as cholinesterase inhibitors. Medicinal Chemistry Research, 2025: 1-19.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
Curated Selection
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