BRCA2-IN-1
BRCA2-IN-1 (Compound 3j) is a potential BRCA2 inhibitor that exhibits antiproliferative activity against the breast cancer MCF-7 cell lines. BRCA2-IN-1 also demonstrates DPPH radical scavenging ability, with an IC50 of 12.36 µM[1].
Product Specifications
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Smiles
O=S(C1=CC=C(/N=N/C2=CC=C(O)C(/C=N/NC(N)=S)=C2)C=C1)(N)=O
Molecular Formula
C14H14N6O3S2
Molecular Weight
378.43
References & Citations
[1]Rezaeianzadeh O, et, al. Synthesis and application of diazenyl sulfonamide-based schiff bases as potential BRCA2 active inhibitors against MCF-7 breast cancer cell line. Sci Rep. 2025 Feb 24;15 (1) :6661.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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