CD13-IN-1
CD13-IN-1 (Compound 5f) is a CD13 inhibitor with an IC50 of 1.71 μM. CD13-IN-1 can inhibit the proliferation of multiple tumor cells and has anti-tumor activity[1].
Product Specifications
UNSPSC
12352005
Target
Aminopeptidase
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O[C@H]1C(F)(F)[C@H](N2C=CC(NC(CNC([C@@H](NC([C@@H](O)[C@H](N)CC3=CC=CC=C3)=O)CC(C)C)=O)=O)=NC2=O)O[C@@H]1COP(OCC(OC)=O)(N[C@H](C(OC(C)C)=O)C)=O.Cl
Molecular Formula
C36H53ClF2N7O14P
Molecular Weight
912.27
References & Citations
[1]Zhang L, et al. Design, synthesis, and anti-cancer evaluation of the novel conjugate of gemcitabine's ProTide prodrug based on CD13. Bioorg Chem. 2025 Apr;157:108293.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CD13
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