CD13-IN-1

CD13-IN-1 (Compound 5f) is a CD13 inhibitor with an IC50 of 1.71 μM. CD13-IN-1 can inhibit the proliferation of multiple tumor cells and has anti-tumor activity[1].

Product Specifications

UNSPSC

12352005

Target

Aminopeptidase

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O[C@H]1C(F)(F)[C@H](N2C=CC(NC(CNC([C@@H](NC([C@@H](O)[C@H](N)CC3=CC=CC=C3)=O)CC(C)C)=O)=O)=NC2=O)O[C@@H]1COP(OCC(OC)=O)(N[C@H](C(OC(C)C)=O)C)=O.Cl

Molecular Formula

C36H53ClF2N7O14P

Molecular Weight

912.27

References & Citations

[1]Zhang L, et al. Design, synthesis, and anti-cancer evaluation of the novel conjugate of gemcitabine's ProTide prodrug based on CD13. Bioorg Chem. 2025 Apr;157:108293.