BTK-IN-42
BTK-IN-42 (Compound 11a) is a Btk inhibitor. BTK-IN-42 can effectively inhibit the growth and migration of tumor cells TMD8, with IC50 values of 2.61 and 5.34 μM for TMD8 and T9 cells respectively. It shows promise for research in the field of anti-cancer[1].
Product Specifications
UNSPSC
12352005
Target
Btk
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(N)C1=C(C2=CC=C(C3=CC=C(F)C(OC)=C3)C=C2)N=C(N4CCC(NC(C=C)=O)CC4)C=C1
Molecular Formula
C27H27FN4O3
Molecular Weight
474.53
References & Citations
[1]Cai J, et al. Design, synthesis and anti-tumor activity of BTK inhibitor Orelabrutinib derivatives. Bioorg Chem. 2025 Apr;157:108278.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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