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BTK-IN-42

BTK-IN-42 (Compound 11a) is a Btk inhibitor. BTK-IN-42 can effectively inhibit the growth and migration of tumor cells TMD8, with IC50 values of 2.61 and 5.34 μM for TMD8 and T9 cells respectively. It shows promise for research in the field of anti-cancer[1].

Product Specifications

UNSPSC

12352005

Target

Btk

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C(N)C1=C(C2=CC=C(C3=CC=C(F)C(OC)=C3)C=C2)N=C(N4CCC(NC(C=C)=O)CC4)C=C1

Molecular Formula

C27H27FN4O3

Molecular Weight

474.53

References & Citations

[1]Cai J, et al. Design, synthesis and anti-tumor activity of BTK inhibitor Orelabrutinib derivatives. Bioorg Chem. 2025 Apr;157:108278.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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