FCOB02
FCOB02 is a monoamine oxidase B (MAO-B) ligand. FCOB02 can be labeled as [18F]FCOB02, a 4-methylcoumarin-like targeting probe. [18F]FCOB02 has a high affinity for MAO-B with an IC50 of 10.68 nM. [18F]FCOB02 can be used in specific MAO-B imaging as well as quantitative analysis in vivo[1].
Product Specifications
CAS Number
3064236-41-2
UNSPSC
12352005
Target
Monoamine Oxidase
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C1C=C(C)C(C=CC(OCC2=CN=C(F)C=C2)=C3)=C3O1
Molecular Formula
C16H12FNO3
Molecular Weight
285.27
References & Citations
[1]Zhang Z, et, al. Synthesis and evaluation of a targeted PET radioligand [18F]FCOB02 for monoamine oxidase B. Bioorganic & Medicinal Chemistry Letters. Volume 121, 1 June 2025, 130157.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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