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KDM4 ligand-1

KDM4 ligand-1 is a ligand for target protein (histone lysine demethylase KDM4) for PROTACs. KDM4 ligand-1 can be used in the synthesis of PROTACs (HY-173135) [1].

Product Specifications

UNSPSC

12352005

Target

Histone Demethylase; Ligands for Target Protein for PROTAC

Related Pathways

Epigenetics; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Others

Smiles

O=C(O)C1=CC=NC=C1NC[C@@H]2CCOC3=C2C=CC(N(C4=CC=C(O)C=C4)C)=C3

Molecular Formula

C23H23N3O4

Molecular Weight

405.45

References & Citations

[1]Rao D, et, al. Discovery of a first-in-class PROTAC degrader of histone lysine demethylase KDM4. Eur J Med Chem. 2025 Apr 15:288:117410.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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