α-Glucosidase-IN-86
α-Glucosidase-IN-86 (Compound A4) is an orally active α-glucosidase inhibitor with an IC50 of 2.72 μM. α-Glucosidase-IN-86 has high safety in mice. α-Glucosidase-IN-86 can reduce fasting blood glucose levels, improve glucose tolerance, regulate blood lipids, and has antioxidant effects in diabetic mice. α-Glucosidase-IN-86 can be used for the research of diabetes[1].
Product Specifications
UNSPSC
12352005
Target
Glycosidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Inflammation/Immunology
Smiles
CC1([C@H](CC[C@@]2([C@]3(CC=C4[C@@]5(CC(C)(CC[C@@]5([C@H](O)C[C@]4([C@@]3(CC[C@@]12[H])C)C)C(NCC6=CN(N=N6)C7=CC=C(C(Cl)=C7)Cl)=O)C)[H])[H])C)O)C
Molecular Formula
C39H54Cl2N4O3
Molecular Weight
697.78
References & Citations
[1]Deng H, et al. Design and synthesis of azole derivatives of echinocystic acid as α-glucosidase inhibitors with hypoglycemic activity. Eur J Med Chem. 2025 Feb 22;289:117437.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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