Anti-inflammatory agent 97
Anti-inflammatory agent 97 (Compound 1l), an anti-inflammation agent, can also inhibit oxidative stress. Anti-inflammatory agent 97 can inhibit the colonic shortening and suppress inflammatory symptoms of the colonic tissue in the DSS -induced ulcerative colitis mice model. Anti-inflammatory agent 97 can regulate the inflammation-related TLR4/NF-κB signaling pathway and the oxidative stress-related Nrf2/HO-1 signaling pathway[1].
Product Specifications
UNSPSC
12352005
Target
NF-κB; Toll-like Receptor (TLR)
Related Pathways
Immunology/Inflammation; NF-κB
Field of Research
Inflammation/Immunology
Smiles
OC(C(C(C)(C)C)=C1)=C(C(C)(C)C)C=C1C(N2CCN(C)CC2)C3=CC=CC(C(F)(F)F)=C3
Molecular Formula
C27H37F3N2O
Molecular Weight
462.59
References & Citations
[1]Ren Z, et, al. Design, synthesis and biological evaluation of diarylmethyl amine derivatives with anti-ulcerative colitis activity via inhibiting inflammation and oxidative stress. Eur J Med Chem. 2025 May 5:289:117433.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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