KR019
KR019 is a potent HBV capsid assembly modulator, exhibits potent antiviral activity in HBV-replicating cells. KR019 binds to the hydrophobic pocket at the core protein dimer-dimer interface, misdirecting capsid assembly into genome-free capsids and thereby inhibiting viral replication[1].
Product Specifications
UNSPSC
12352005
Target
HBV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(NC1=CC=C(F)C(C(F)F)=C1)C2=CC(S(=O)(NC3COC3)=O)=C(F)C=C2N
Molecular Formula
C17H15F4N3O4S
Molecular Weight
433.38
References & Citations
[1]Abbas SA, et, al. Development of sulfamoylbenzamide-based capsid assembly modulators for hepatitis B virus capsid assembly. Eur J Med Chem. 2025 Jun 5:290:117430.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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