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KR019

KR019 is a potent HBV capsid assembly modulator, exhibits potent antiviral activity in HBV-replicating cells. KR019 binds to the hydrophobic pocket at the core protein dimer-dimer interface, misdirecting capsid assembly into genome-free capsids and thereby inhibiting viral replication[1].

Product Specifications

UNSPSC

12352005

Target

HBV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(NC1=CC=C(F)C(C(F)F)=C1)C2=CC(S(=O)(NC3COC3)=O)=C(F)C=C2N

Molecular Formula

C17H15F4N3O4S

Molecular Weight

433.38

References & Citations

[1]Abbas SA, et, al. Development of sulfamoylbenzamide-based capsid assembly modulators for hepatitis B virus capsid assembly. Eur J Med Chem. 2025 Jun 5:290:117430.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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