HBV-IN-51
HBV-IN-51 (Compound 17e) is a potent HBV capsid assembly modulator. HBV-IN-51 exhibits remarkable anti-HBV activity with an EC50 of 0.033 μM in HepAD38 cells. HBV-IN-51 exhibits robust metabolic stability in plasma, and can be rapidly metabolized in human liver microsomes[1].
Product Specifications
UNSPSC
12352005
Target
HBV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
S=C(N(C)C(C)C)NC1=CC(C(NC2=CC(F)=C(F)C(F)=C2)=O)=C(C3CC3)C=C1F
Molecular Formula
C21H21F4N3OS
Molecular Weight
439.47
References & Citations
[1]Wang M, et, al. Design and biochemical evaluation of 2-cyclopropyl-thioureidobenzamide (CP-TBA) derivatives as potent HBV capsid assembly modulators targeting a novel binding site. Eur J Med Chem. 2025 May 5:289:117441.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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