NCATS-SM7270
NCATS-SM7270 is a highly specific NOX2 inhibitor, with an IC50 of 4.09 μM. NCATS-SM7270 protects mice from mild traumatic brain injury[1].
Product Specifications
UNSPSC
12352005
Target
NADPH Oxidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Smiles
CN1C2=C(C=CC(C3=CN(C4CC4)C5=NC=CC(NS(=O)(C6=NN(C)C=C6)=O)=C35)=C2)C=C1
Molecular Formula
C23H22N6O2S
Molecular Weight
446.52
References & Citations
[1]Mason H, et al. Development of an improved and specific inhibitor of NADPH oxidase 2 to treat traumatic brain injury. Redox Biol. 2023 Apr;60:102611.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NOX2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![ERCC1 Mouse Monoclonal Antibody [Clone ID: OTI5E6]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
