MDA7
MDA7 is the selective agonist for cannabinoid receptor 2 with EC50 of 128 nM and 67.4 nM in human CB2 receptor and rat CB2 receptor. MDA7 exhibits good affinity to human CB2 receptor and rat CB2 receptor with Ki of 422 nM and 238 nM. MDA7 exhibits analgesic activity in rats models[1].
Product Specifications
CAS Number
[1103840-28-3]
UNSPSC
12352005
Target
Cannabinoid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(N1CCCCC1)C2=CC=C3C(OCC3(CC4=CC=CC=C4)C)=C2
Molecular Formula
C22H25NO2
Molecular Weight
335.44
References & Citations
[1]Naguib M, et al., MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain models. Br J Pharmacol. 2008 Dec;155 (7) :1104-16.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-173083/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CB1; CB2
Curated Selection
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