TLR7 agonist 30
TLR7 agonist 30 (compound 2) is an agent-linker conjugate for ADC. TLR7 agonist 30 contains a TLR7 agonist (compound 1) and a cleavable linker, and has potent anti-tumor activity[1].
Product Specifications
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC; Toll-like Receptor (TLR)
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OC1=NC2=C(N)N=C(OCCCC)N=C2N1CC3=CN=C(CN(C4CCC4)C(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCN)=O)=O)=O)C=C5C(NCCNC(CCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)=O)C=C3
Molecular Formula
C71H115N15O22
Molecular Weight
1530.76
References & Citations
[1]Sega E, et al. Targeted Delivery of TLR7 Agonists to the Tumor Microenvironment Enhances Tumor Immunity via Activation of Tumor-Resident Myeloid Cells. Bioconjug Chem. 2025 Feb 13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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