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SJPYT-310

SJPYT-310 is a selective PXR antagonist. SJPYT-310 shows no significant cytotoxicity[1].

Product Specifications

CAS Number

[2883814-84-2]

UNSPSC

12352005

Target

Orphan Receptor; Pregnane X Receptor (PXR)

Related Pathways

GPCR/G Protein; Vitamin D Related/Nuclear Receptor

Field of Research

Others

Purity

99.9

Smiles

CC(C)(C)C1=CC=C(O[C@@H](C)CCC)C(NC(C2=C(C)N(C3=C(OC)C=CC(C)=C3)N=N2)=O)=C1

Molecular Formula

C27H36N4O3

Molecular Weight

464.60

References & Citations

[1]Garcia-Maldonado E, et al. Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR. Nat Commun. 2024 May 14;15 (1) :4054.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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