DprE1-IN-13
DprE1-IN-13 (Compound 42) is the inhibitor for decaprenyl-phosphoryl-β-d-ribose oxidase (DprE1) with IC50 of 12.72 μM. DprE1-IN-13 inhibits Mycobacterium tuberculosis H37Ra with MIC50 of 1.071 μM[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(NN/C=C1C(N(CC#C)C(NC/1=O)=O)=O)C2=CC=NC=C2
Molecular Formula
C14H11N5O4
Molecular Weight
313.27
References & Citations
[1]Liang J, et al., Discovery of novel pyrimidinetrione derivatives as DprE1 inhibitors with potent antimycobacterial activities. Eur J Med Chem. 2025 Feb 18;289:117416.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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